| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| alkB | apbA/panE | RPA1722 | RPA4562 | Alkylated DNA repair protein. | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.626 |
| alkB | hpd | RPA1722 | RPA0005 | Alkylated DNA repair protein. | 4-hydroxyphenylpyruvate dioxygenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.413 |
| alkB | panE | RPA1722 | RPA1943 | Alkylated DNA repair protein. | Putative ketopantoate reductase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.626 |
| alkB | panE1 | RPA1722 | RPA0020 | Alkylated DNA repair protein. | Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.626 |
| apbA/panE | alkB | RPA4562 | RPA1722 | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Alkylated DNA repair protein. | 0.626 |
| apbA/panE | guaC | RPA4562 | RPA4561 | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.575 |
| apbA/panE | hpd | RPA4562 | RPA0005 | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 4-hydroxyphenylpyruvate dioxygenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.401 |
| apbA/panE | panB | RPA4562 | RPA3098 | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.990 |
| apbA/panE | panC | RPA4562 | RPA3155 | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Putative pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.960 |
| apbA/panE | panE | RPA4562 | RPA1943 | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Putative ketopantoate reductase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.928 |
| apbA/panE | panE1 | RPA4562 | RPA0020 | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.928 |
| apbA/panE | ribB | RPA4562 | RPA1093 | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Possible GTP cyclohydrolase II, riboflavin biosynthesis; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.435 |
| guaC | apbA/panE | RPA4561 | RPA4562 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.575 |
| guaC | ribB | RPA4561 | RPA1093 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Possible GTP cyclohydrolase II, riboflavin biosynthesis; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.818 |
| hpd | alkB | RPA0005 | RPA1722 | 4-hydroxyphenylpyruvate dioxygenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Alkylated DNA repair protein. | 0.413 |
| hpd | apbA/panE | RPA0005 | RPA4562 | 4-hydroxyphenylpyruvate dioxygenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.401 |
| hpd | panE | RPA0005 | RPA1943 | 4-hydroxyphenylpyruvate dioxygenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative ketopantoate reductase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.401 |
| hpd | panE1 | RPA0005 | RPA0020 | 4-hydroxyphenylpyruvate dioxygenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.401 |
| panB | apbA/panE | RPA3098 | RPA4562 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.990 |
| panB | panC | RPA3098 | RPA3155 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Putative pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.999 |