Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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otsAPutative alpha,alpha-trehalose-phosphate synthase (UDP-forming) (trehalose-6-phosphate synthase); Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family. (493 aa)    
Predicted Functional Partners:
otsB
Putative trehalose-6-phosphate phophatase, biosynthetic; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
 0.999
exoN
UTP-glucose-1-phosphate uridylyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
    
 0.929
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
    
 0.862
RPA3640
Glycoside hydrolase, family 15.
 
   
 0.857
wbnF
Nucleotide sugar epimerase.
     
 0.801
rfbF
alpha-D-glucose-1-phosphate cytidylyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
     
  0.800
RPA3643
Putative trehalose synthase.
 
  
 0.729
RPA2100
Possible hydrolase.
   
    0.643
tal
Putative Transaldolase Phosphoglucose isomerase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
  
 0.624
katE
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
  
 0.571
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
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