STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (448 aa)    
Predicted Functional Partners:
maiA
Putative maleylacetoacetate isomerase.
 
 
 0.998
hpd
4-hydroxyphenylpyruvate dioxygenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 
 0.997
fahA
Fumarylacetoacetate hydrolase.
  
 0.994
cphA1
Putative beta lactamase precursor.
 
  
 0.906
RPA4675
Possible 3-(3-hydroxy-phenyl)propionate hydroxylase.
 
  
 0.869
RPA4674
Conserved hypothetical protein.
 
     0.779
hpaD
Putative 3,4-dihydroxyphenylacetate 2,3-dioxygenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
      
 0.752
RPA1229
Probable aerobic phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
     
 0.751
RPA3443
Possible isomerase/decarboxylase.
  
  
 0.718
phhB
Putative pterin-4-alpha-carbinolamine dehydratase; 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1).
  
  
 0.700
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
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