| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA0675 | RPA0676 | RPA0675 | RPA0676 | Possible hydrolases (alpha/beta hydrolase superfamily). | Possible enoyl-CoA hydratase/isomerase family member. | 0.937 |
| RPA0675 | RPA0677 | RPA0675 | RPA0677 | Possible hydrolases (alpha/beta hydrolase superfamily). | Hypothetical protein. | 0.867 |
| RPA0675 | aroK-2 | RPA0675 | RPA4787 | Possible hydrolases (alpha/beta hydrolase superfamily). | Possible Shikimate kinase with a Helix-turn-helix domain; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.780 |
| RPA0675 | badA | RPA0675 | RPA0661 | Possible hydrolases (alpha/beta hydrolase superfamily). | benzoate-CoA ligase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.757 |
| RPA0675 | hbaA | RPA0675 | RPA0669 | Possible hydrolases (alpha/beta hydrolase superfamily). | 4-hydroxybenzoate-CoA ligase; Catalyzes the ligation of 4-hydroxybenzoate, benzoate or cyclohex-1,4-dienecarboxylate and CoA at the expense of ATP. The enzyme shows low activity towards cyclo-2,5-dienecarboxylate, 4- fluorobenzoate, 4-chlorobenzoate and 2-methoxybenzoate. Belongs to the ATP-dependent AMP-binding enzyme family. Benzoate-CoA ligase subfamily. | 0.786 |
| RPA0676 | RPA0675 | RPA0676 | RPA0675 | Possible enoyl-CoA hydratase/isomerase family member. | Possible hydrolases (alpha/beta hydrolase superfamily). | 0.937 |
| RPA0676 | RPA0677 | RPA0676 | RPA0677 | Possible enoyl-CoA hydratase/isomerase family member. | Hypothetical protein. | 0.993 |
| RPA0676 | aroK-2 | RPA0676 | RPA4787 | Possible enoyl-CoA hydratase/isomerase family member. | Possible Shikimate kinase with a Helix-turn-helix domain; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.829 |
| RPA0676 | badA | RPA0676 | RPA0661 | Possible enoyl-CoA hydratase/isomerase family member. | benzoate-CoA ligase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.848 |
| RPA0676 | hbaA | RPA0676 | RPA0669 | Possible enoyl-CoA hydratase/isomerase family member. | 4-hydroxybenzoate-CoA ligase; Catalyzes the ligation of 4-hydroxybenzoate, benzoate or cyclohex-1,4-dienecarboxylate and CoA at the expense of ATP. The enzyme shows low activity towards cyclo-2,5-dienecarboxylate, 4- fluorobenzoate, 4-chlorobenzoate and 2-methoxybenzoate. Belongs to the ATP-dependent AMP-binding enzyme family. Benzoate-CoA ligase subfamily. | 0.819 |
| RPA0677 | RPA0675 | RPA0677 | RPA0675 | Hypothetical protein. | Possible hydrolases (alpha/beta hydrolase superfamily). | 0.867 |
| RPA0677 | RPA0676 | RPA0677 | RPA0676 | Hypothetical protein. | Possible enoyl-CoA hydratase/isomerase family member. | 0.993 |
| RPA0677 | aroK-2 | RPA0677 | RPA4787 | Hypothetical protein. | Possible Shikimate kinase with a Helix-turn-helix domain; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.818 |
| RPA0677 | badA | RPA0677 | RPA0661 | Hypothetical protein. | benzoate-CoA ligase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.794 |
| RPA0677 | hbaA | RPA0677 | RPA0669 | Hypothetical protein. | 4-hydroxybenzoate-CoA ligase; Catalyzes the ligation of 4-hydroxybenzoate, benzoate or cyclohex-1,4-dienecarboxylate and CoA at the expense of ATP. The enzyme shows low activity towards cyclo-2,5-dienecarboxylate, 4- fluorobenzoate, 4-chlorobenzoate and 2-methoxybenzoate. Belongs to the ATP-dependent AMP-binding enzyme family. Benzoate-CoA ligase subfamily. | 0.797 |
| RPA2210 | aroK-2 | RPA2210 | RPA4787 | Conserved unknown protein; COGs COG3550. | Possible Shikimate kinase with a Helix-turn-helix domain; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.894 |
| RPA4052 | aroA | RPA4052 | RPA0061 | Possible 3-dehydroquinate synthase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.994 |
| RPA4052 | aroB | RPA4052 | RPA0503 | Possible 3-dehydroquinate synthase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.925 |
| RPA4052 | aroC | RPA4052 | RPA1201 | Possible 3-dehydroquinate synthase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.991 |
| RPA4052 | aroK-2 | RPA4052 | RPA4787 | Possible 3-dehydroquinate synthase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Possible Shikimate kinase with a Helix-turn-helix domain; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.979 |