node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Psyc_0768 | gcvH | Psyc_0768 | Psyc_0798 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.968 |
Psyc_0768 | gcvP | Psyc_0768 | Psyc_0796 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.942 |
Psyc_0768 | gcvT | Psyc_0768 | Psyc_0799 | Dihydrolipoamide dehydrogenase. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.947 |
Psyc_0768 | glnA | Psyc_0768 | Psyc_0975 | Dihydrolipoamide dehydrogenase. | L-glutamine synthetase; Contains adenylation site. | 0.816 |
Psyc_0768 | gltB | Psyc_0768 | Psyc_1874 | Dihydrolipoamide dehydrogenase. | Glutamate synthase (NADPH) large subunit; This orf aligns best with NADPH-dependent glutamate synthase proteins as opposed to proteins that use other cofactors. | 0.881 |
Psyc_0768 | glyA | Psyc_0768 | Psyc_0290 | Dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.913 |
Psyc_0768 | lpdG | Psyc_0768 | Psyc_0104 | Dihydrolipoamide dehydrogenase. | Dihydrolipoamide dehydrogenase. | 0.928 |
Psyc_0768 | sgaA | Psyc_0768 | Psyc_1388 | Dihydrolipoamide dehydrogenase. | Serine-glyoxylate aminotransferase apoenzyme. | 0.900 |
gcvH | Psyc_0768 | Psyc_0798 | Psyc_0768 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide dehydrogenase. | 0.968 |
gcvH | gcvP | Psyc_0798 | Psyc_0796 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
gcvH | gcvT | Psyc_0798 | Psyc_0799 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
gcvH | glnA | Psyc_0798 | Psyc_0975 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | L-glutamine synthetase; Contains adenylation site. | 0.819 |
gcvH | gltB | Psyc_0798 | Psyc_1874 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glutamate synthase (NADPH) large subunit; This orf aligns best with NADPH-dependent glutamate synthase proteins as opposed to proteins that use other cofactors. | 0.889 |
gcvH | glyA | Psyc_0798 | Psyc_0290 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.961 |
gcvH | lpdG | Psyc_0798 | Psyc_0104 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide dehydrogenase. | 0.967 |
gcvH | sgaA | Psyc_0798 | Psyc_1388 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine-glyoxylate aminotransferase apoenzyme. | 0.905 |
gcvP | Psyc_0768 | Psyc_0796 | Psyc_0768 | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Dihydrolipoamide dehydrogenase. | 0.942 |
gcvP | gcvH | Psyc_0796 | Psyc_0798 | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
gcvP | gcvT | Psyc_0796 | Psyc_0799 | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
gcvP | glnA | Psyc_0796 | Psyc_0975 | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | L-glutamine synthetase; Contains adenylation site. | 0.889 |