node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Psyc_1668 | aroA | Psyc_1668 | Psyc_1184 | Anthranilate synthase, component II. | 3-phosphoshikimate 1-carboxyvinyltransferase / prephenate dehydrogenase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.562 |
Psyc_1668 | aroB | Psyc_1668 | Psyc_1877 | Anthranilate synthase, component II. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.413 |
Psyc_1668 | aroC | Psyc_1668 | Psyc_1455 | Anthranilate synthase, component II. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.942 |
Psyc_1668 | aroE | Psyc_1668 | Psyc_0139 | Anthranilate synthase, component II. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.593 |
Psyc_1668 | aroK | Psyc_1668 | Psyc_1878 | Anthranilate synthase, component II. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.401 |
Psyc_1668 | pabB | Psyc_1668 | Psyc_1900 | Anthranilate synthase, component II. | Possible p-aminobenzoate synthase, component I. | 0.999 |
Psyc_1668 | pheA | Psyc_1668 | Psyc_1186 | Anthranilate synthase, component II. | Prephenate dehydratase; Contains 3 domains: chorismate mutase, prephenate dehydratase, and an ACT (amino acid synthesis regulatory domain). This enzyme is bifunctional in the phenylalanine synthesis pathway. | 0.948 |
Psyc_1668 | trpE | Psyc_1668 | Psyc_1667 | Anthranilate synthase, component II. | Anthranilate synthase, component I. | 0.999 |
Psyc_1668 | trpG | Psyc_1668 | Psyc_0974 | Anthranilate synthase, component II. | Anthranilate synthase, component II. | 0.816 |
Psyc_1668 | ubiC | Psyc_1668 | Psyc_0289 | Anthranilate synthase, component II. | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.801 |
aroA | Psyc_1668 | Psyc_1184 | Psyc_1668 | 3-phosphoshikimate 1-carboxyvinyltransferase / prephenate dehydrogenase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Anthranilate synthase, component II. | 0.562 |
aroA | aroB | Psyc_1184 | Psyc_1877 | 3-phosphoshikimate 1-carboxyvinyltransferase / prephenate dehydrogenase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.997 |
aroA | aroC | Psyc_1184 | Psyc_1455 | 3-phosphoshikimate 1-carboxyvinyltransferase / prephenate dehydrogenase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.997 |
aroA | aroE | Psyc_1184 | Psyc_0139 | 3-phosphoshikimate 1-carboxyvinyltransferase / prephenate dehydrogenase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.918 |
aroA | aroK | Psyc_1184 | Psyc_1878 | 3-phosphoshikimate 1-carboxyvinyltransferase / prephenate dehydrogenase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.989 |
aroA | pabB | Psyc_1184 | Psyc_1900 | 3-phosphoshikimate 1-carboxyvinyltransferase / prephenate dehydrogenase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Possible p-aminobenzoate synthase, component I. | 0.582 |
aroA | pheA | Psyc_1184 | Psyc_1186 | 3-phosphoshikimate 1-carboxyvinyltransferase / prephenate dehydrogenase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Prephenate dehydratase; Contains 3 domains: chorismate mutase, prephenate dehydratase, and an ACT (amino acid synthesis regulatory domain). This enzyme is bifunctional in the phenylalanine synthesis pathway. | 0.998 |
aroA | trpE | Psyc_1184 | Psyc_1667 | 3-phosphoshikimate 1-carboxyvinyltransferase / prephenate dehydrogenase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Anthranilate synthase, component I. | 0.570 |
aroA | trpG | Psyc_1184 | Psyc_0974 | 3-phosphoshikimate 1-carboxyvinyltransferase / prephenate dehydrogenase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Anthranilate synthase, component II. | 0.567 |
aroA | ubiC | Psyc_1184 | Psyc_0289 | 3-phosphoshikimate 1-carboxyvinyltransferase / prephenate dehydrogenase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.874 |