node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Psyc_0767 | ispA | Psyc_0767 | Psyc_1935 | Small-conductance mechanosensitive ion channel. | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.490 |
Psyc_1936 | ispA | Psyc_1936 | Psyc_1935 | Conserved hypothetical protein; The function of the DUF72 family is unknown. Aquifex aeolicus has two copies of this protein. A probable aspartyl-tRNA synthetase from Escherichia coli [1] belongs to this group. | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.639 |
Psyc_1956 | ispA | Psyc_1956 | Psyc_1935 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.518 |
Psyc_1956 | ispB | Psyc_1956 | Psyc_1574 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Probable octaprenyl-diphosphate synthase; Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.677) with cleavage site probability 0.297 at residue 22; Belongs to the FPP/GGPP synthase family. | 0.518 |
cumB | ispA | Psyc_1496 | Psyc_1935 | tRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.518 |
dxs | ispA | Psyc_0221 | Psyc_1935 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.509 |
dxs | lytB | Psyc_0221 | Psyc_1722 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.721 |
ispA | Psyc_0767 | Psyc_1935 | Psyc_0767 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Small-conductance mechanosensitive ion channel. | 0.490 |
ispA | Psyc_1936 | Psyc_1935 | Psyc_1936 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Conserved hypothetical protein; The function of the DUF72 family is unknown. Aquifex aeolicus has two copies of this protein. A probable aspartyl-tRNA synthetase from Escherichia coli [1] belongs to this group. | 0.639 |
ispA | Psyc_1956 | Psyc_1935 | Psyc_1956 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 0.518 |
ispA | cumB | Psyc_1935 | Psyc_1496 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | tRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.518 |
ispA | dxs | Psyc_1935 | Psyc_0221 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.509 |
ispA | ispB | Psyc_1935 | Psyc_1574 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Probable octaprenyl-diphosphate synthase; Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.677) with cleavage site probability 0.297 at residue 22; Belongs to the FPP/GGPP synthase family. | 0.924 |
ispA | lytB | Psyc_1935 | Psyc_1722 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.927 |
ispA | mutL | Psyc_1935 | Psyc_0919 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | DNA mismatch repair protein MutL; The mutL protein binds to mutS, which recognizes and binds to mismatches in DNA duplexes. The mutS-mutL-DNA complex stimulates mutH to cleave the unmethylated DNA strand at the GATC sequence; Contains following domains: DNA mismatch repair protein:ATP-binding region, ATPase-like. | 0.591 |
ispA | mutS | Psyc_1935 | Psyc_0247 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.479 |
ispA | uppS | Psyc_1935 | Psyc_1533 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.961 |
ispB | Psyc_1956 | Psyc_1574 | Psyc_1956 | Probable octaprenyl-diphosphate synthase; Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.677) with cleavage site probability 0.297 at residue 22; Belongs to the FPP/GGPP synthase family. | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 0.518 |
ispB | ispA | Psyc_1574 | Psyc_1935 | Probable octaprenyl-diphosphate synthase; Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.677) with cleavage site probability 0.297 at residue 22; Belongs to the FPP/GGPP synthase family. | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.924 |
ispB | uppS | Psyc_1574 | Psyc_1533 | Probable octaprenyl-diphosphate synthase; Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.677) with cleavage site probability 0.297 at residue 22; Belongs to the FPP/GGPP synthase family. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.961 |