node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mbur_0935 | glyA | Mbur_0935 | Mbur_1813 | Phosphoserine phosphatase; Evidence code ER2. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.955 |
Mbur_0935 | trpA | Mbur_0935 | Mbur_0109 | Phosphoserine phosphatase; Evidence code ER2. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.910 |
Mbur_0935 | trpB1 | Mbur_0935 | Mbur_0108 | Phosphoserine phosphatase; Evidence code ER2. | Tryptophan synthase beta chain 1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.932 |
Mbur_0935 | trpB2 | Mbur_0935 | Mbur_1100 | Phosphoserine phosphatase; Evidence code ER2. | Tryptophan synthase beta chain 2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
Mbur_0935 | trpC | Mbur_0935 | Mbur_0107 | Phosphoserine phosphatase; Evidence code ER2. | Indole-3-glycerol phosphate synthase; Evidence code ER2; Belongs to the TrpC family. | 0.425 |
Mbur_0935 | trpD | Mbur_0935 | Mbur_2363 | Phosphoserine phosphatase; Evidence code ER2. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.456 |
acnB | glyA | Mbur_0316 | Mbur_1813 | Aconitate hydratase 2; Evidence code ER2. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.645 |
acnB | trpA | Mbur_0316 | Mbur_0109 | Aconitate hydratase 2; Evidence code ER2. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.910 |
acnB | trpB1 | Mbur_0316 | Mbur_0108 | Aconitate hydratase 2; Evidence code ER2. | Tryptophan synthase beta chain 1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.937 |
acnB | trpC | Mbur_0316 | Mbur_0107 | Aconitate hydratase 2; Evidence code ER2. | Indole-3-glycerol phosphate synthase; Evidence code ER2; Belongs to the TrpC family. | 0.825 |
acnB | trpD | Mbur_0316 | Mbur_2363 | Aconitate hydratase 2; Evidence code ER2. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.839 |
acnB | trpE | Mbur_0316 | Mbur_2365 | Aconitate hydratase 2; Evidence code ER2. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.835 |
acnB | trpF | Mbur_0316 | Mbur_2364 | Aconitate hydratase 2; Evidence code ER2. | N-(5'-phosphoribosyl)anthranilate isomerase; Evidence code ER2; PRAI; Belongs to the TrpF family. | 0.919 |
glyA | Mbur_0935 | Mbur_1813 | Mbur_0935 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase; Evidence code ER2. | 0.955 |
glyA | acnB | Mbur_1813 | Mbur_0316 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aconitate hydratase 2; Evidence code ER2. | 0.645 |
glyA | trpA | Mbur_1813 | Mbur_0109 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.942 |
glyA | trpB1 | Mbur_1813 | Mbur_0108 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain 1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.944 |
glyA | trpB2 | Mbur_1813 | Mbur_1100 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain 2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.911 |
glyA | trpE | Mbur_1813 | Mbur_2365 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.663 |
glyA | trpG | Mbur_1813 | Mbur_2366 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Anthranilate synthase component II; Evidence code ER2. | 0.451 |