node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mbur_0861 | Mbur_1847 | Mbur_0861 | Mbur_1847 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, nickel-inserting subunit; Evidence code ER3. | Methylenetetrahydrofolate reductase; Evidence code ER3. | 0.494 |
Mbur_0861 | cdhA | Mbur_0861 | Mbur_0858 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, nickel-inserting subunit; Evidence code ER3. | Acetyl-CoA decarbonylase/synthase complex alpha subunit 2; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. | 0.927 |
Mbur_0861 | cdhB | Mbur_0861 | Mbur_0859 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, nickel-inserting subunit; Evidence code ER3. | Acetyl-CoA decarbonylase/synthase complex epsilon subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD- mediated CO oxidation. | 0.942 |
Mbur_0861 | cdhC | Mbur_0861 | Mbur_0860 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, nickel-inserting subunit; Evidence code ER3. | Acetyl-CoA decarbonylase/synthase complex beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex). | 0.986 |
Mbur_0861 | cdhD | Mbur_0861 | Mbur_0862 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, nickel-inserting subunit; Evidence code ER3. | Acetyl-CoA decarbonylase/synthase complex delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex. | 0.987 |
Mbur_0861 | cdhE | Mbur_0861 | Mbur_0863 | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, nickel-inserting subunit; Evidence code ER3. | Acetyl-CoA decarbonylase/synthase complex gamma subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. | 0.981 |
Mbur_1137 | Mbur_2158 | Mbur_1137 | Mbur_2158 | Acetyl-coenzyme A synthetase; Evidence code ER2; Acetate--CoA ligase. | Pyruvate synthase beta chain; Evidence code ER2; pyruvate:ferredoxin oxidoreductase beta subunit. | 0.919 |
Mbur_1137 | acsA | Mbur_1137 | Mbur_0999 | Acetyl-coenzyme A synthetase; Evidence code ER2; Acetate--CoA ligase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.903 |
Mbur_1137 | cdhC | Mbur_1137 | Mbur_0860 | Acetyl-coenzyme A synthetase; Evidence code ER2; Acetate--CoA ligase. | Acetyl-CoA decarbonylase/synthase complex beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex). | 0.927 |
Mbur_1137 | cdhD | Mbur_1137 | Mbur_0862 | Acetyl-coenzyme A synthetase; Evidence code ER2; Acetate--CoA ligase. | Acetyl-CoA decarbonylase/synthase complex delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex. | 0.924 |
Mbur_1137 | cdhE | Mbur_1137 | Mbur_0863 | Acetyl-coenzyme A synthetase; Evidence code ER2; Acetate--CoA ligase. | Acetyl-CoA decarbonylase/synthase complex gamma subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. | 0.918 |
Mbur_1847 | Mbur_0861 | Mbur_1847 | Mbur_0861 | Methylenetetrahydrofolate reductase; Evidence code ER3. | Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, nickel-inserting subunit; Evidence code ER3. | 0.494 |
Mbur_1847 | cdhA | Mbur_1847 | Mbur_0858 | Methylenetetrahydrofolate reductase; Evidence code ER3. | Acetyl-CoA decarbonylase/synthase complex alpha subunit 2; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. | 0.428 |
Mbur_1847 | cdhC | Mbur_1847 | Mbur_0860 | Methylenetetrahydrofolate reductase; Evidence code ER3. | Acetyl-CoA decarbonylase/synthase complex beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex). | 0.695 |
Mbur_1847 | cdhD | Mbur_1847 | Mbur_0862 | Methylenetetrahydrofolate reductase; Evidence code ER3. | Acetyl-CoA decarbonylase/synthase complex delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex. | 0.989 |
Mbur_1847 | cdhE | Mbur_1847 | Mbur_0863 | Methylenetetrahydrofolate reductase; Evidence code ER3. | Acetyl-CoA decarbonylase/synthase complex gamma subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. | 0.969 |
Mbur_2158 | Mbur_1137 | Mbur_2158 | Mbur_1137 | Pyruvate synthase beta chain; Evidence code ER2; pyruvate:ferredoxin oxidoreductase beta subunit. | Acetyl-coenzyme A synthetase; Evidence code ER2; Acetate--CoA ligase. | 0.919 |
Mbur_2158 | acsA | Mbur_2158 | Mbur_0999 | Pyruvate synthase beta chain; Evidence code ER2; pyruvate:ferredoxin oxidoreductase beta subunit. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.919 |
Mbur_2158 | cdhC | Mbur_2158 | Mbur_0860 | Pyruvate synthase beta chain; Evidence code ER2; pyruvate:ferredoxin oxidoreductase beta subunit. | Acetyl-CoA decarbonylase/synthase complex beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex). | 0.927 |
Mbur_2158 | cdhD | Mbur_2158 | Mbur_0862 | Pyruvate synthase beta chain; Evidence code ER2; pyruvate:ferredoxin oxidoreductase beta subunit. | Acetyl-CoA decarbonylase/synthase complex delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex. | 0.918 |