node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mbur_0787 | hisA | Mbur_0787 | Mbur_1332 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; Evidence code ER2. | 0.671 |
Mbur_0787 | hisB | Mbur_0787 | Mbur_1333 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | Imidazoleglycerol-phosphate dehydratase; Evidence code ER2. | 0.755 |
Mbur_0787 | hisD | Mbur_0787 | Mbur_1103 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.736 |
Mbur_0787 | hisE | Mbur_0787 | Mbur_1885 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | Phosphoribosyl-ATP pyrophosphatase; Evidence code ER2. | 0.646 |
Mbur_0787 | hisF | Mbur_0787 | Mbur_1857 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | Imidazoleglycerol-phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.718 |
Mbur_0787 | hisG | Mbur_0787 | Mbur_1331 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.720 |
Mbur_0787 | hisH | Mbur_0787 | Mbur_1801 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.723 |
Mbur_0787 | hisI | Mbur_0787 | Mbur_1790 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.718 |
cobD | cobD-2 | Mbur_2087 | Mbur_2089 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | 0.941 |
cobD | hisA | Mbur_2087 | Mbur_1332 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; Evidence code ER2. | 0.712 |
cobD | hisB | Mbur_2087 | Mbur_1333 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | Imidazoleglycerol-phosphate dehydratase; Evidence code ER2. | 0.743 |
cobD | hisD | Mbur_2087 | Mbur_1103 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.755 |
cobD | hisE | Mbur_2087 | Mbur_1885 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | Phosphoribosyl-ATP pyrophosphatase; Evidence code ER2. | 0.646 |
cobD | hisF | Mbur_2087 | Mbur_1857 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | Imidazoleglycerol-phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.725 |
cobD | hisG | Mbur_2087 | Mbur_1331 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.672 |
cobD | hisH | Mbur_2087 | Mbur_1801 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.740 |
cobD | hisI | Mbur_2087 | Mbur_1790 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.717 |
cobD-2 | cobD | Mbur_2089 | Mbur_2087 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | 0.941 |
cobD-2 | hisA | Mbur_2089 | Mbur_1332 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; Evidence code ER2. | 0.671 |
cobD-2 | hisB | Mbur_2089 | Mbur_1333 | L-threonine O-3-phosphate decarboxylase; Evidence code ER3. | Imidazoleglycerol-phosphate dehydratase; Evidence code ER2. | 0.737 |