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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mbur_1908Protein of unknown function UCP019164; Evidence code ER4. (310 aa)    
Predicted Functional Partners:
Mbur_1905
Protein of unknown function UCP018781; Evidence code ER4.
 
     0.950
Mbur_1904
Protein of unknown function UCP005642; Evidence code ER4.
 
     0.948
Mbur_1907
Hypothetical protein; Evidence code ER5.
 
     0.948
Mbur_1903
Protein of unknown function UPF0288; Evidence code ER4; Belongs to the UPF0288 family.
 
     0.947
Mbur_1906
2-hydroxyglutaryl-CoA dehydratase component A; Evidence code ER3.
 
     0.947
Mbur_1902
Methylcoenzyme M reductase system component A2; Evidence code ER2.
 
     0.933
Mbur_1909
Carboxymuconolactone decarboxylase-domain protein; Evidence code ER4.
 
     0.867
mcrC
Highly conserved methyl-coenzyme M reductase operon protein C with unknown function; Evidence code ER4.
 
     0.781
mcrA
Methyl-coenzyme M reductase, subunit alpha; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
     0.759
mcrB
Methyl-coenzyme M reductase, subunit beta; Evidence code ER2.
 
     0.758
Your Current Organism:
Methanococcoides burtonii
NCBI taxonomy Id: 259564
Other names: M. burtonii DSM 6242, Methanococcoides burtonii DSM 6242, Methanococcoides burtonii str. DSM 6242
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