STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
secEPreprotein translocase subunit secE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (69 aa)    
Predicted Functional Partners:
secY
Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
 
 0.960
rpl26e
LSU ribosomal protein L26e; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
 
  
 0.911
rpl31e
LSU ribosomal protein L31E; Evidence code ER2; Belongs to the ribosomal protein L31e family.
 
   0.906
rpl11p
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
   0.898
rpl10e
LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
   0.856
rpl44e
LSU ribosomal protein L44E; Binds to the 23S rRNA.
  
   0.853
Mbur_1579
Transmembrane oligosaccharyl transferase; Evidence code ER3.
  
 
 
 0.853
rpl24p
LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
 
 0.834
rplX
LSU ribosomal protein LX; Evidence code ER2.
  
   0.832
rpl32e
LSU ribosomal protein L32E; Evidence code ER2; Belongs to the eukaryotic ribosomal protein eL32 family.
  
   0.829
Your Current Organism:
Methanococcoides burtonii
NCBI taxonomy Id: 259564
Other names: M. burtonii DSM 6242, Methanococcoides burtonii DSM 6242, Methanococcoides burtonii str. DSM 6242
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.