STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
secFPreprotein translocase SecF subunit; Involved in protein export. (300 aa)    
Predicted Functional Partners:
secD
Protein-export membrane protein secD; Involved in protein export.
 
 0.999
Mbur_1988
Replication factor C small subunit; Evidence code ER2.
       0.766
Mbur_1734
Peptidase S24-like protein; Evidence code ER4.
 
  
 0.748
Mbur_1989
Elongator complex protein 3; Evidence code ER2.
       0.708
Mbur_0974
Sec-independent protein translocase; Evidence code ER4.
  
  
 0.661
Mbur_1985
dCMP deaminase; Evidence code ER2.
       0.595
atpE
V-type ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
     0.566
thrS
Threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr); Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.561
hisS
Histidyl-tRNA synthetase; Evidence code ER3; Belongs to the class-II aminoacyl-tRNA synthetase family.
     
 0.513
srp54
Signal recognition particle SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
  
 0.501
Your Current Organism:
Methanococcoides burtonii
NCBI taxonomy Id: 259564
Other names: M. burtonii DSM 6242, Methanococcoides burtonii DSM 6242, Methanococcoides burtonii str. DSM 6242
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.