node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCW44611.1 | SCW72998.1 | SAMN02927928_1288 | SAMN02927928_3011 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. | Acetolactate synthase, large subunit. | 0.906 |
SCW44611.1 | SCW75471.1 | SAMN02927928_1288 | SAMN02927928_3167 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.649 |
SCW44611.1 | SCW76297.1 | SAMN02927928_1288 | SAMN02927928_3258 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.899 |
SCW44611.1 | SCW80551.1 | SAMN02927928_1288 | SAMN02927928_3557 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. | Homoserine dehydrogenase. | 0.824 |
SCW44611.1 | leuB | SAMN02927928_1288 | SAMN02927928_3006 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.949 |
SCW72998.1 | SCW44611.1 | SAMN02927928_3011 | SAMN02927928_1288 | Acetolactate synthase, large subunit. | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. | 0.906 |
SCW72998.1 | SCW75392.1 | SAMN02927928_3011 | SAMN02927928_3157 | Acetolactate synthase, large subunit. | Threonine synthase. | 0.415 |
SCW72998.1 | SCW75471.1 | SAMN02927928_3011 | SAMN02927928_3167 | Acetolactate synthase, large subunit. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.649 |
SCW72998.1 | SCW76297.1 | SAMN02927928_3011 | SAMN02927928_3258 | Acetolactate synthase, large subunit. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.947 |
SCW72998.1 | SCW80551.1 | SAMN02927928_3011 | SAMN02927928_3557 | Acetolactate synthase, large subunit. | Homoserine dehydrogenase. | 0.824 |
SCW72998.1 | leuB | SAMN02927928_3011 | SAMN02927928_3006 | Acetolactate synthase, large subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.987 |
SCW75392.1 | SCW72998.1 | SAMN02927928_3157 | SAMN02927928_3011 | Threonine synthase. | Acetolactate synthase, large subunit. | 0.415 |
SCW75392.1 | SCW75471.1 | SAMN02927928_3157 | SAMN02927928_3167 | Threonine synthase. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.876 |
SCW75392.1 | SCW76297.1 | SAMN02927928_3157 | SAMN02927928_3258 | Threonine synthase. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.975 |
SCW75392.1 | SCW80551.1 | SAMN02927928_3157 | SAMN02927928_3557 | Threonine synthase. | Homoserine dehydrogenase. | 0.999 |
SCW75392.1 | SCW83677.1 | SAMN02927928_3157 | SAMN02927928_0090 | Threonine synthase. | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.912 |
SCW75392.1 | leuB | SAMN02927928_3157 | SAMN02927928_3006 | Threonine synthase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.583 |
SCW75471.1 | SCW44611.1 | SAMN02927928_3167 | SAMN02927928_1288 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. | 0.649 |
SCW75471.1 | SCW72998.1 | SAMN02927928_3167 | SAMN02927928_3011 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Acetolactate synthase, large subunit. | 0.649 |
SCW75471.1 | SCW75392.1 | SAMN02927928_3167 | SAMN02927928_3157 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Threonine synthase. | 0.876 |