STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFN49774.1Dihydrofolate reductase. (205 aa)    
Predicted Functional Partners:
SFM97281.1
Dihydrofolate reductase.
 
     0.722
SFN49722.1
Signal transduction histidine kinase.
       0.678
SFN49754.1
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains.
       0.678
SFO09878.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.662
SFO58923.1
Aminomethyltransferase; Belongs to the GcvT family.
    
 0.620
SFO48559.1
Rifamycin polyketide synthase modules 1, 2 and 3.
  
 
 0.539
SFO03926.1
Dihydrofolate reductase.
 
     0.469
SFO13719.1
Hypothetical protein.
 
     0.422
Your Current Organism:
Pseudonocardia ammonioxydans
NCBI taxonomy Id: 260086
Other names: CIP 109186, DSM 44958, JCM 12462, P. ammonioxydans, Pseudonocardia ammonioxydans Liu et al. 2006, Pseudonocardia sp. H9, strain H9
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