node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AQQ66429.1 | AQQ66430.1 | Mag101_01280 | Mag101_01285 | Metal-dependent phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.984 |
AQQ66429.1 | AQQ66431.1 | Mag101_01280 | Mag101_01290 | Metal-dependent phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.639 |
AQQ66429.1 | AQQ69311.1 | Mag101_01280 | Mag101_01310 | Metal-dependent phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.403 |
AQQ66429.1 | hemC | Mag101_01280 | Mag101_01295 | Metal-dependent phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.631 |
AQQ66430.1 | AQQ66429.1 | Mag101_01285 | Mag101_01280 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Metal-dependent phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.984 |
AQQ66430.1 | AQQ66431.1 | Mag101_01285 | Mag101_01290 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.973 |
AQQ66430.1 | cysG | Mag101_01285 | Mag101_08570 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.913 |
AQQ66430.1 | hemC | Mag101_01285 | Mag101_01295 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.698 |
AQQ66430.1 | hemE | Mag101_01285 | Mag101_01400 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.907 |
AQQ66431.1 | AQQ66429.1 | Mag101_01290 | Mag101_01280 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Metal-dependent phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.639 |
AQQ66431.1 | AQQ66430.1 | Mag101_01290 | Mag101_01285 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.973 |
AQQ66431.1 | AQQ66433.1 | Mag101_01290 | Mag101_01300 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Holliday junction resolvase RuvX; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.630 |
AQQ66431.1 | AQQ68918.1 | Mag101_01290 | Mag101_15735 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | 0.834 |
AQQ66431.1 | AQQ69311.1 | Mag101_01290 | Mag101_01310 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Energy transducer TonB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.550 |
AQQ66431.1 | cysG | Mag101_01290 | Mag101_08570 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.973 |
AQQ66431.1 | hemA | Mag101_01290 | Mag101_04575 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.713 |
AQQ66431.1 | hemC | Mag101_01290 | Mag101_01295 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.996 |
AQQ66431.1 | hemE | Mag101_01290 | Mag101_01400 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.936 |
AQQ66431.1 | hemL | Mag101_01290 | Mag101_15730 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.573 |
AQQ66433.1 | AQQ66431.1 | Mag101_01300 | Mag101_01290 | Holliday junction resolvase RuvX; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.630 |