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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQQ68390.1Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)    
Predicted Functional Partners:
AQQ67383.1
Glutathione-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.859
grpE
Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
 
  
 0.796
AQQ67689.1
Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.796
hslU
HslU--HslV peptidase ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
  
 
 0.780
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
 
 
 0.764
hslV
ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
  
  
 0.761
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
  
 
 0.733
AQQ68389.1
NGG1p interacting factor NIF3; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.719
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.669
AQQ68277.1
Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.612
Your Current Organism:
Microbulbifer agarilyticus
NCBI taxonomy Id: 260552
Other names: DSM 19200, JCM 14708, M. agarilyticus, Microbulbifer agarilyticus Miyazaki et al. 2008, Microbulbifer sp. JAMB-A3, Microbulbifer sp. JAMM 0654, Microbulbifer sp. JAMM 0793, strain JAMB A3
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