| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQQ66727.1 | AQQ68287.1 | Mag101_03030 | Mag101_12010 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | 0.518 |
| AQQ66727.1 | birA | Mag101_03030 | Mag101_14990 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.591 |
| AQQ66727.1 | gmk | Mag101_03030 | Mag101_17365 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.556 |
| AQQ66727.1 | nadA | Mag101_03030 | Mag101_13830 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. | 0.554 |
| AQQ66823.1 | AQQ68287.1 | Mag101_03585 | Mag101_12010 | NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | 0.623 |
| AQQ66823.1 | nadA | Mag101_03585 | Mag101_13830 | NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. | 0.671 |
| AQQ68035.1 | AQQ68287.1 | Mag101_10595 | Mag101_12010 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | 0.996 |
| AQQ68035.1 | birA | Mag101_10595 | Mag101_14990 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.526 |
| AQQ68035.1 | nadA | Mag101_10595 | Mag101_13830 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. | 0.998 |
| AQQ68287.1 | AQQ66727.1 | Mag101_12010 | Mag101_03030 | Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.518 |
| AQQ68287.1 | AQQ66823.1 | Mag101_12010 | Mag101_03585 | Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.623 |
| AQQ68287.1 | AQQ68035.1 | Mag101_12010 | Mag101_10595 | Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.996 |
| AQQ68287.1 | birA | Mag101_12010 | Mag101_14990 | Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.526 |
| AQQ68287.1 | nadA | Mag101_12010 | Mag101_13830 | Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. | 0.997 |
| AQQ68287.1 | purL | Mag101_12010 | Mag101_05285 | Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.452 |
| AQQ69013.1 | AQQ69586.1 | Mag101_16280 | Mag101_13595 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.904 |
| AQQ69013.1 | nadA | Mag101_16280 | Mag101_13830 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. | 0.597 |
| AQQ69586.1 | AQQ69013.1 | Mag101_13595 | Mag101_16280 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.904 |
| AQQ69586.1 | nadA | Mag101_13595 | Mag101_13830 | Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. | 0.597 |
| birA | AQQ66727.1 | Mag101_14990 | Mag101_03030 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.591 |