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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQQ68916.1Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)    
Predicted Functional Partners:
thiC
Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
 
 0.985
thiE
Phosphomethylpyrimidine kinase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
0.975
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.842
AQQ68369.1
Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.694
AQQ66591.1
3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.679
AQQ69557.1
Thiamine biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.632
AQQ68915.1
TIGR00701 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.575
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.574
AQQ68918.1
Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.
     
 0.525
AQQ68914.1
Chloride transporter ClC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.464
Your Current Organism:
Microbulbifer agarilyticus
NCBI taxonomy Id: 260552
Other names: DSM 19200, JCM 14708, M. agarilyticus, Microbulbifer agarilyticus Miyazaki et al. 2008, Microbulbifer sp. JAMB-A3, Microbulbifer sp. JAMM 0654, Microbulbifer sp. JAMM 0793, strain JAMB A3
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