STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AU385_07090Xanthine permease. (430 aa)    
Predicted Functional Partners:
AU385_07085
Uricase.
  
 0.917
uraH
5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
  
 0.873
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
 0.851
AU385_07095
Uric acid permease PucJ.
 
   
0.849
allB
Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
  
  
 0.693
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.684
pyrR
Pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
  
  
 0.684
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.645
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.633
AU385_07100
PucR family transcriptional regulator.
  
  
 0.599
Your Current Organism:
Bacillus halotolerans
NCBI taxonomy Id: 260554
Other names: ATCC 25096, B. halotolerans, Bacillus axarquiensis, Bacillus axarquiensis Ruiz-Garcia et al. 2005 emend. Dunlap et al. 2016, Bacillus malacitensis, Bacillus malacitensis Ruiz-Garcia et al. 2005, Brevibacterium halotolerans, CCUG 47676, CECT 5687 [[Bacillus malacitensis]], CECT 5688 [[Bacillus axarquiensis]], CIP 108772 [[Bacillus axarquiensis]], CIP 67.21, DSM 8802, JCM 12400, LMG 22476 [[Bacillus axarquiensis]], LMG 22477 [[Bacillus malacitensis]], LMG:22476 [[Bacillus axarquiensis]], LMG:22477 [[Bacillus malacitensis]], NRRL B-41617 [[Bacillus axarquiensis]], strain CR-119 [[Bacillus axarquiensis]], strain CR-95 [[Bacillus malacitensis]]
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