STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRK50586.1Aldo-keto reductase. (331 aa)    
Predicted Functional Partners:
aqpZ
Aquaporin Z; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.801
dnaJ
Chaperone protein DnaJ 1; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
    
 
 0.709
dnaJ-2
Co-factor of molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwe [...]
    
 
 0.709
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
   0.704
ppiB
Putative peptidyl-prolyl cis-trans isomerase B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
    
   0.703
ppiB-2
Putative peptidyl-prolyl cis-trans isomerase B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
    
   0.703
ppiA
Putative peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.703
CRK50673.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
    
   0.702
pstP
PP2C-family Ser/Thr phosphatase.
    
   0.702
dkgA
2,5-diketo-D-gluconate reductase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
0.696
Your Current Organism:
Rhodococcus sp. RD62
NCBI taxonomy Id: 260936
Other names: R. sp. RD6.2, Rhodococcus sp. RD6.2
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