node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CRK52935.1 | carA | RHCRD62_50138 | RHCRD62_50137 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. | 0.975 |
CRK52935.1 | pyrAB | RHCRD62_50138 | RHCRD62_50136 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Pyrimidine-specific carbamoyl-phosphate synthetase (large subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family. | 0.999 |
CRK52935.1 | pyrB | RHCRD62_50138 | RHCRD62_50140 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.988 |
CRK52935.1 | pyrC | RHCRD62_50138 | RHCRD62_50139 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.988 |
CRK52935.1 | pyrD | RHCRD62_50138 | RHCRD62_20458 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.823 |
CRK52935.1 | pyrE | RHCRD62_50138 | RHCRD62_40131 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.727 |
CRK52935.1 | pyrF | RHCRD62_50138 | RHCRD62_50135 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.978 |
CRK52935.1 | pyrR | RHCRD62_50138 | RHCRD62_50141 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Transcriptional attenuator and uracil phosphoribosyltransferase activity; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.972 |
CRK52935.1 | upp | RHCRD62_50138 | RHCRD62_110034 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Uracil phosphoribosyltransferase; Belongs to the UPRTase family. | 0.487 |
carA | CRK52935.1 | RHCRD62_50137 | RHCRD62_50138 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.975 |
carA | pyrAB | RHCRD62_50137 | RHCRD62_50136 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. | Pyrimidine-specific carbamoyl-phosphate synthetase (large subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family. | 0.999 |
carA | pyrB | RHCRD62_50137 | RHCRD62_50140 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | RHCRD62_50137 | RHCRD62_50139 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
carA | pyrD | RHCRD62_50137 | RHCRD62_20458 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.896 |
carA | pyrE | RHCRD62_50137 | RHCRD62_40131 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.840 |
carA | pyrF | RHCRD62_50137 | RHCRD62_50135 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.988 |
carA | pyrH | RHCRD62_50137 | RHCRD62_80190 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.710 |
carA | pyrR | RHCRD62_50137 | RHCRD62_50141 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. | Transcriptional attenuator and uracil phosphoribosyltransferase activity; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.979 |
carA | upp | RHCRD62_50137 | RHCRD62_110034 | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. | Uracil phosphoribosyltransferase; Belongs to the UPRTase family. | 0.578 |
pyrAB | CRK52935.1 | RHCRD62_50136 | RHCRD62_50138 | Pyrimidine-specific carbamoyl-phosphate synthetase (large subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.999 |