node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A3K91_0002 | A3K91_0491 | A3K91_0002 | A3K91_0491 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Cell division protein FtsK; Pfam:pfam01580 FtsK/SpoIIIE family. | 0.529 |
A3K91_0002 | A3K91_1018 | A3K91_0002 | A3K91_1018 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Chromosome (Plasmid) partitioning protein ParB; Pfam:pfam02195 ParB-like nuclease domain; Belongs to the ParB family. | 0.527 |
A3K91_0002 | A3K91_1467 | A3K91_0002 | A3K91_1467 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.484 |
A3K91_0002 | dnaA | A3K91_0002 | A3K91_0001 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.979 |
A3K91_0002 | recF | A3K91_0002 | A3K91_0003 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA recombination protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.891 |
A3K91_0002 | recR | A3K91_0002 | A3K91_1774 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Recombinase RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.454 |
A3K91_0002 | rpoB | A3K91_0002 | A3K91_2426 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.592 |
A3K91_0002 | smpB | A3K91_0002 | A3K91_0411 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.581 |
A3K91_0491 | A3K91_0002 | A3K91_0491 | A3K91_0002 | Cell division protein FtsK; Pfam:pfam01580 FtsK/SpoIIIE family. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.529 |
A3K91_0491 | A3K91_1017 | A3K91_0491 | A3K91_1017 | Cell division protein FtsK; Pfam:pfam01580 FtsK/SpoIIIE family. | Chromosome (Plasmid) partitioning protein ParA; Pfam:pfam01656 CobQ/CobB/MinD/ParA nucleotide binding domain. | 0.728 |
A3K91_0491 | A3K91_1018 | A3K91_0491 | A3K91_1018 | Cell division protein FtsK; Pfam:pfam01580 FtsK/SpoIIIE family. | Chromosome (Plasmid) partitioning protein ParB; Pfam:pfam02195 ParB-like nuclease domain; Belongs to the ParB family. | 0.833 |
A3K91_0491 | A3K91_1467 | A3K91_0491 | A3K91_1467 | Cell division protein FtsK; Pfam:pfam01580 FtsK/SpoIIIE family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.422 |
A3K91_0491 | dnaA | A3K91_0491 | A3K91_0001 | Cell division protein FtsK; Pfam:pfam01580 FtsK/SpoIIIE family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.709 |
A3K91_0491 | recR | A3K91_0491 | A3K91_1774 | Cell division protein FtsK; Pfam:pfam01580 FtsK/SpoIIIE family. | Recombinase RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.583 |
A3K91_1017 | A3K91_0491 | A3K91_1017 | A3K91_0491 | Chromosome (Plasmid) partitioning protein ParA; Pfam:pfam01656 CobQ/CobB/MinD/ParA nucleotide binding domain. | Cell division protein FtsK; Pfam:pfam01580 FtsK/SpoIIIE family. | 0.728 |
A3K91_1017 | A3K91_1018 | A3K91_1017 | A3K91_1018 | Chromosome (Plasmid) partitioning protein ParA; Pfam:pfam01656 CobQ/CobB/MinD/ParA nucleotide binding domain. | Chromosome (Plasmid) partitioning protein ParB; Pfam:pfam02195 ParB-like nuclease domain; Belongs to the ParB family. | 0.988 |
A3K91_1017 | dnaA | A3K91_1017 | A3K91_0001 | Chromosome (Plasmid) partitioning protein ParA; Pfam:pfam01656 CobQ/CobB/MinD/ParA nucleotide binding domain. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.648 |
A3K91_1017 | recR | A3K91_1017 | A3K91_1774 | Chromosome (Plasmid) partitioning protein ParA; Pfam:pfam01656 CobQ/CobB/MinD/ParA nucleotide binding domain. | Recombinase RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.491 |
A3K91_1018 | A3K91_0002 | A3K91_1018 | A3K91_0002 | Chromosome (Plasmid) partitioning protein ParB; Pfam:pfam02195 ParB-like nuclease domain; Belongs to the ParB family. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.527 |
A3K91_1018 | A3K91_0491 | A3K91_1018 | A3K91_0491 | Chromosome (Plasmid) partitioning protein ParB; Pfam:pfam02195 ParB-like nuclease domain; Belongs to the ParB family. | Cell division protein FtsK; Pfam:pfam01580 FtsK/SpoIIIE family. | 0.833 |