node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A3K91_0466 | A3K91_0467 | A3K91_0466 | A3K91_0467 | D-2-hydroxyglutarate dehydrogenase; Pfam:pfam02913 FAD linked oxidases, C-terminal domain. | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 0.555 |
A3K91_0467 | A3K91_0466 | A3K91_0467 | A3K91_0466 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | D-2-hydroxyglutarate dehydrogenase; Pfam:pfam02913 FAD linked oxidases, C-terminal domain. | 0.555 |
A3K91_0467 | A3K91_0515 | A3K91_0467 | A3K91_0515 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.551 |
A3K91_0467 | A3K91_2392 | A3K91_0467 | A3K91_2392 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | Phosphoserine phosphatase; Pfam:pfam00702 haloacid dehalogenase-like hydrolase. | 0.578 |
A3K91_0467 | gpmI | A3K91_0467 | A3K91_1917 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.904 |
A3K91_0467 | rplB | A3K91_0467 | A3K91_0570 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.510 |
A3K91_0467 | rplF | A3K91_0467 | A3K91_0582 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.567 |
A3K91_0467 | rplU | A3K91_0467 | A3K91_1949 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.507 |
A3K91_0467 | rpmA | A3K91_0467 | A3K91_1948 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | Pfam:pfam01016 Ribosomal L27 protein; Belongs to the bacterial ribosomal protein bL27 family. | 0.508 |
A3K91_0467 | rpsO | A3K91_0467 | A3K91_0093 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.524 |
A3K91_0467 | serC | A3K91_0467 | A3K91_1432 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.980 |
A3K91_0515 | A3K91_0467 | A3K91_0515 | A3K91_0467 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 0.551 |
A3K91_0515 | A3K91_2392 | A3K91_0515 | A3K91_2392 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoserine phosphatase; Pfam:pfam00702 haloacid dehalogenase-like hydrolase. | 0.458 |
A3K91_0515 | serC | A3K91_0515 | A3K91_1432 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.416 |
A3K91_2392 | A3K91_0467 | A3K91_2392 | A3K91_0467 | Phosphoserine phosphatase; Pfam:pfam00702 haloacid dehalogenase-like hydrolase. | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 0.578 |
A3K91_2392 | A3K91_0515 | A3K91_2392 | A3K91_0515 | Phosphoserine phosphatase; Pfam:pfam00702 haloacid dehalogenase-like hydrolase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.458 |
A3K91_2392 | serC | A3K91_2392 | A3K91_1432 | Phosphoserine phosphatase; Pfam:pfam00702 haloacid dehalogenase-like hydrolase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.955 |
gpmI | A3K91_0467 | A3K91_1917 | A3K91_0467 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 0.904 |
rplB | A3K91_0467 | A3K91_0570 | A3K91_0467 | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 0.510 |
rplB | rplF | A3K91_0570 | A3K91_0582 | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.998 |