STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A3K91_0872Pfam:pfam07023 Protein of unknown function (DUF1315). (103 aa)    
Predicted Functional Partners:
msrB
Peptide methionine sulfoxide reductase MsrB; Pfam:pfam01641 SelR domain; Belongs to the MsrB Met sulfoxide reductase family.
  
    0.871
A3K91_0128
Pfam:pfam01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit.
  
    0.765
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
     0.756
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
     0.750
msrA
Thiol:disulfide oxidoreductase associated with MetSO reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
    0.741
A3K91_2098
tRNA-(Ms[2]io[6]A)-hydroxylase; Pfam:pfam06175 tRNA-(2-methylthio-N-6-isopentenyl-adenosine)-hydroxylase (MiaE).
  
     0.715
A3K91_0595
Pfam:pfam04315 Protein of unknown function, DUF462.
  
     0.691
A3K91_2389
Pfam:pfam03695 Uncharacterized protein family (UPF0149); Belongs to the UPF0149 family.
  
     0.689
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
     0.682
ubiC
Putative chorismate pyruvate-lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.
  
     0.631
Your Current Organism:
Psychrobacter alimentarius
NCBI taxonomy Id: 261164
Other names: DSM 16065, JCM 12315, KCTC 12186, P. alimentarius, Psychrobacter alimentarius Yoon et al. 2005, strain JG-100
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