STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A3K91_0993Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. (549 aa)    
Predicted Functional Partners:
A3K91_0132
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.946
A3K91_1009
Dihydrolipoamide acetyltransferase; Pfam:pfam00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain).
 0.942
A3K91_1717
Pfam:pfam00293 NUDIX domain.
     
 0.931
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 0.918
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.915
cobB
NAD-dependent protein deacylase; Pfam:pfam02146 Sir2 family; Belongs to the sirtuin family. Class III subfamily.
  
 0.913
A3K91_2287
Nicotinamide-nucleotide adenylyltransferase; Pfam:pfam13521 AAA domain.
 
  
 0.913
A3K91_0633
NAD(P) transhydrogenase alpha subunit; Pfam:pfam12769 Domain of unknown function (DUF3814).
     
 0.911
A3K91_0634
NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
   
 
 0.906
A3K91_0149
Pfam:pfam03819 MazG nucleotide pyrophosphohydrolase domain.
    
 0.905
Your Current Organism:
Psychrobacter alimentarius
NCBI taxonomy Id: 261164
Other names: DSM 16065, JCM 12315, KCTC 12186, P. alimentarius, Psychrobacter alimentarius Yoon et al. 2005, strain JG-100
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