STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIVB_1Stage IV sporulation protein B. (335 aa)    
Predicted Functional Partners:
spo0A
Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
   
 0.939
CUO59393.1
Stage II sporulation protein P.
  
   
 0.835
CUO82491.1
Stage III sporulation protein AD.
 
     0.819
spoIIIAE
Stage III sporulation-related protein.
 
     0.815
CUO82577.1
Stage III sporulation protein AA.
 
     0.814
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.808
gpr
Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
    0.806
CUP28922.1
Stage II sporulation protein.
  
   
 0.805
sigF_1
Sporulation sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.803
spoIIID
Stage III sporulation protein D.
  
   
 0.803
Your Current Organism:
Intestinibacter bartlettii
NCBI taxonomy Id: 261299
Other names: ATCC BAA-827, CCUG 48940, Clostridium bartlettii, Clostridium bartlettii Song et al. 2004, DSM 16795, I. bartlettii, Intestinibacter bartlettii (Song et al. 2004) Gerritsen et al. 2014, WAL 16138
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