STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUP05862.1Stage V sporulation protein AC. (159 aa)    
Predicted Functional Partners:
spoVAD
Stage V sporulation protein AD.
 
  
 0.989
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
   
 0.899
spoIIAA
Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
   
 0.885
gpr
Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.874
sigF_2
RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.862
spoVAE
Stage V sporulation protein AE.
 
  
0.854
spoIVA
Stage IV sporulation protein A.
  
   
 0.808
spoIIID
Stage III sporulation protein D.
  
   
 0.794
CUP28922.1
Stage II sporulation protein.
  
   
 0.784
sigF_1
Sporulation sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.782
Your Current Organism:
Intestinibacter bartlettii
NCBI taxonomy Id: 261299
Other names: ATCC BAA-827, CCUG 48940, Clostridium bartlettii, Clostridium bartlettii Song et al. 2004, DSM 16795, I. bartlettii, Intestinibacter bartlettii (Song et al. 2004) Gerritsen et al. 2014, WAL 16138
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