STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUP17415.1CRISPR-associated Cas4 family protein. (172 aa)    
Predicted Functional Partners:
cas2
CRISPR-associated endoribonuclease Cas2.
 
 
 
 0.990
CUP17432.1
CRISPR-associated protein Cas1.
 
 
 
 0.978
cas3
CRISPR-associated nuclease/helicase Cas3.
 
  
 0.919
cst2
CRISPR-associated regulatory protein Cst2.
 
   
 0.910
cas5
CRISPR-associated protein Cas5.
 
   
 0.910
cas6
CRISPR-associated endoribonuclease Cas6.
 
   
 0.901
cst1
CRISPR-associated CXXC_CXXC protein Cst1.
 
   
 0.894
cas1
CRISPR-associated Cas1 family protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 
 0.789
cas2-2
CRISPR-associated Cas2 family protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
   
 
 0.689
CUO71524.1
CRISPR-associated helicase Cas3.
 
  
 0.673
Your Current Organism:
Intestinibacter bartlettii
NCBI taxonomy Id: 261299
Other names: ATCC BAA-827, CCUG 48940, Clostridium bartlettii, Clostridium bartlettii Song et al. 2004, DSM 16795, I. bartlettii, Intestinibacter bartlettii (Song et al. 2004) Gerritsen et al. 2014, WAL 16138
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