node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CUP29241.1 | CUP29346.1 | ERS852493_02444 | ERS852493_02447 | UPF0489 domain. | Protein of uncharacterised function (DUF3298). | 0.435 |
CUP29241.1 | rlmI | ERS852493_02444 | ERS852493_02446 | UPF0489 domain. | Putative SAM-dependent methyltransferase. | 0.732 |
CUP29241.1 | rluD_3 | ERS852493_02444 | ERS852493_02445 | UPF0489 domain. | Pseudouridylate synthase. | 0.727 |
CUP29241.1 | secA_2 | ERS852493_02444 | ERS852493_02443 | UPF0489 domain. | SEC-C motif domain-containing protein. | 0.592 |
CUP29346.1 | CUP29241.1 | ERS852493_02447 | ERS852493_02444 | Protein of uncharacterised function (DUF3298). | UPF0489 domain. | 0.435 |
CUP29346.1 | rlmI | ERS852493_02447 | ERS852493_02446 | Protein of uncharacterised function (DUF3298). | Putative SAM-dependent methyltransferase. | 0.458 |
CUP29346.1 | rluD_3 | ERS852493_02447 | ERS852493_02445 | Protein of uncharacterised function (DUF3298). | Pseudouridylate synthase. | 0.458 |
glyA | rlmI | ERS852493_00101 | ERS852493_02446 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative SAM-dependent methyltransferase. | 0.427 |
glyA | rpsK | ERS852493_00101 | ERS852493_02704 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.410 |
ribD | rlmI | ERS852493_01418 | ERS852493_02446 | Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Putative SAM-dependent methyltransferase. | 0.457 |
rlmI | CUP29241.1 | ERS852493_02446 | ERS852493_02444 | Putative SAM-dependent methyltransferase. | UPF0489 domain. | 0.732 |
rlmI | CUP29346.1 | ERS852493_02446 | ERS852493_02447 | Putative SAM-dependent methyltransferase. | Protein of uncharacterised function (DUF3298). | 0.458 |
rlmI | glyA | ERS852493_02446 | ERS852493_00101 | Putative SAM-dependent methyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.427 |
rlmI | ribD | ERS852493_02446 | ERS852493_01418 | Putative SAM-dependent methyltransferase. | Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.457 |
rlmI | rluD_3 | ERS852493_02446 | ERS852493_02445 | Putative SAM-dependent methyltransferase. | Pseudouridylate synthase. | 0.932 |
rlmI | rpsK | ERS852493_02446 | ERS852493_02704 | Putative SAM-dependent methyltransferase. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.770 |
rlmI | secA_2 | ERS852493_02446 | ERS852493_02443 | Putative SAM-dependent methyltransferase. | SEC-C motif domain-containing protein. | 0.559 |
rlmI | yncF | ERS852493_02446 | ERS852493_00330 | Putative SAM-dependent methyltransferase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.442 |
rluD_3 | CUP29241.1 | ERS852493_02445 | ERS852493_02444 | Pseudouridylate synthase. | UPF0489 domain. | 0.727 |
rluD_3 | CUP29346.1 | ERS852493_02445 | ERS852493_02447 | Pseudouridylate synthase. | Protein of uncharacterised function (DUF3298). | 0.458 |