STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa)    
Predicted Functional Partners:
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
 
 0.999
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
 
 0.991
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.
 
 
 0.990
purN
Phosphoribosylglycinamide formyltransferase-1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
 
 0.990
SJZ31479.1
Phosphoribosylformylglycinamidine synthase.
 
  
 0.980
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
 
 0.976
SJZ49856.1
Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase; Belongs to the PurH family.
 
  
 0.955
SJZ31864.1
Adenylosuccinate lyase.
  
 
 0.951
SJZ68858.1
Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.938
SJZ31562.1
Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase.
  
  
 0.851
Your Current Organism:
Treponema porcinum
NCBI taxonomy Id: 261392
Other names: ATCC BAA-908, CIP 108245, JCM 12342, T. porcinum, Treponema porcinum Nordhoff et al. 2005, Treponema sp. 14V28, strain 14V28
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