STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GBAA_0842Identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382. (171 aa)    
Predicted Functional Partners:
GBAA_0843
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
   0.983
rsbW
Anti-sigma b factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
  
    0.858
rsbV
Anti sigma b factor antagonist RsbV; Identified by match to protein family HMM PF01740; match to protein family HMM TIGR00377; Belongs to the anti-sigma-factor antagonist family.
  
    0.830
sigB
RNA polymerase sigma-B factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.816
GBAA_0988
Conserved hypothetical protein; Identified by match to protein family HMM PF04226.
  
  
 0.800
GBAA_1000
Hypothetical protein; Identified by Glimmer3; putative.
   
    0.785
GBAA_0999
Conserved hypothetical protein.
  
    0.781
tpx
Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
  
 
 0.756
GBAA_0986
Conserved hypothetical protein.
   
  
 0.712
GBAA_0997
Hypothetical protein; Identified by Glimmer3; putative.
   
  
 0.690
Your Current Organism:
Bacillus anthracis
NCBI taxonomy Id: 261594
Other names: B. anthracis str. 'Ames Ancestor', Bacillus anthracis str. 'Ames Ancestor', Bacillus anthracis str. Ames 0581, Bacillus anthracis str. Ames Ancestor
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.