STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GBAA_1554Conserved hypothetical protein; Identified by match to protein family HMM PF03819. (123 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
  
    0.928
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
  
  
 0.905
bshA
Glycosyl transferase, group 1 family protein; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway, the formation of N-acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate.
 
  
 0.846
cca
tRNA nucleotidyltransferase/poly(A) polymerase family protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
  
 0.835
bshB1
Conserved hypothetical protein; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Belongs to the PIGL family.
 
  
 0.818
birA
birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.786
dnaD
DNA replication protein DnaD; Identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446.
 
     0.652
GBAA_0030
Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
    0.470
GBAA_1553
Putative membrane protein; Identified by match to protein family HMM PF02588.
       0.435
GBAA_1542
Conserved hypothetical protein; Identified by match to protein family HMM PF08858; match to protein family HMM PF08864; Belongs to the UPF0302 family.
 
     0.402
Your Current Organism:
Bacillus anthracis
NCBI taxonomy Id: 261594
Other names: B. anthracis str. 'Ames Ancestor', Bacillus anthracis str. 'Ames Ancestor', Bacillus anthracis str. Ames 0581, Bacillus anthracis str. Ames Ancestor
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.