STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GBAA_2111Identified by match to protein family HMM PF00903. (127 aa)    
Predicted Functional Partners:
GBAA_3399
Identified by match to protein family HMM PF00903.
  
  
  0.913
GBAA_5135
D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 0.909
GBAA_2538
Metallo-beta-lactamase/rhodanese-like domain protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00753.
  
 
 0.904
GBAA_5452
Conserved hypothetical protein; Identified by match to protein family HMM PF00903.
  
  
 
0.901
GBAA_3011
Identified by match to protein family HMM PF00903.
   
 
  0.900
GBAA_3208
Identified by match to protein family HMM PF00903.
     
  0.900
GBAA_4485
Identified by match to protein family HMM PF00753.
     
  0.900
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
  0.821
tdcB
Threonine ammonia-lyase, catabolic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
  0.817
ilvA
Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
  0.816
Your Current Organism:
Bacillus anthracis
NCBI taxonomy Id: 261594
Other names: B. anthracis str. 'Ames Ancestor', Bacillus anthracis str. 'Ames Ancestor', Bacillus anthracis str. Ames 0581, Bacillus anthracis str. Ames Ancestor
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