STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDH35566.1Protease I. (186 aa)    
Predicted Functional Partners:
tpx
Thiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
  
 
 0.783
SDH23966.1
Superoxide dismutase, Cu-Zn family.
   
 0.747
rpsJ
SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
   0.701
rplN
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.672
SDH35510.1
Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains.
 
    0.650
SDH29350.1
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 0.624
rplE
LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
   
   0.618
rpsS
SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
   0.616
SDH35462.1
Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family.
  
    0.547
SDH66208.1
Fe-S oxidoreductase.
    
  0.536
Your Current Organism:
Winogradskyella thalassocola
NCBI taxonomy Id: 262004
Other names: Bacteroidetes bacterium KMM 3907, DSM 15363, KCTC 12221, KMM 3907, LMG 22492, LMG:22492, W. thalassocola, Winogradskyella thalassocola Nedashkovskaya et al. 2005 emend. Nedashkovskaya et al. 2012
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.