STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDI21081.1Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa)    
Predicted Functional Partners:
dut
dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
 
 
 0.963
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.954
coaX
Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
 
 
 0.949
SDI21127.1
Protein of unknown function.
      0.936
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 
 0.907
SDH03766.1
Aspartate aminotransferase.
  
  0.885
SDH07703.1
Aspartate aminotransferase.
  
  0.885
SDI21158.1
DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
    0.840
SDI21050.1
RNA polymerase Rpb6.
  
    0.815
SDI20999.1
Beta-barrel assembly machine subunit BamD.
 
     0.810
Your Current Organism:
Winogradskyella thalassocola
NCBI taxonomy Id: 262004
Other names: Bacteroidetes bacterium KMM 3907, DSM 15363, KCTC 12221, KMM 3907, LMG 22492, LMG:22492, W. thalassocola, Winogradskyella thalassocola Nedashkovskaya et al. 2005 emend. Nedashkovskaya et al. 2012
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.