STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OAB88552.1Serine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)    
Predicted Functional Partners:
ilvD
Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family.
  
  
 0.847
LhgO
Hydroxyglutarate oxidase; Catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.794
OAB88553.1
Thiamine biosynthesis protein ThiJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.774
IlvN
Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.770
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.710
GltB
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.708
OAB89077.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.645
OAB88551.1
Siderophore utilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.586
OAB86641.1
Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.578
OAB89075.1
Disulfide bond formation protein DsbA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.570
Your Current Organism:
Janibacter melonis
NCBI taxonomy Id: 262209
Other names: DSM 16063, J. melonis, JCM 12321, Janibacter melonis Yoon et al. 2004, KCTC 9987, NBRC 107855, strain CM2104
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