STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHF98782.1Ribonucleoside-diphosphate reductase beta chain. (324 aa)    
Predicted Functional Partners:
SHF98755.1
Ribonucleoside-diphosphate reductase alpha chain.
 
 0.998
SHH54798.1
Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.981
SHH15028.1
Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 0.980
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.861
cmk
Cytidylate kinase.
    
 0.835
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.824
SHH70296.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.823
adk-2
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.816
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.815
SHG45534.1
ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.
  
 
 0.792
Your Current Organism:
Flavobacterium frigidimaris
NCBI taxonomy Id: 262320
Other names: Cytophaga sp. KUC-1, DSM 15937, F. frigidimaris, Flavobacterium frigidimaris Nogi et al. 2005, JCM 12218, strain KUC-1
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