kynA protein (Lysobacter gummosus) - STRING interaction network

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kynA

Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (291 aa)

Predicted Functional Partners:

kynU

0.987

ALN90418.1

0.953

trpA

0.810

trpB

0.800

hppD

0.534

ALN93177.1

0.523

ALN93181.1

0.487

ALN93179.1

0.475

ALN94184.1

0.447

Your Current Organism:

Lysobacter gummosus

NCBI taxonomy Id: 262324
Other names: ATCC 29489, DSM 6980, KCTC 12132, L. gummosus, LMG 8763, LMG:8763, Lysobacter sp. OeWu101, UASM 402

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALN90418.1	kynA	LG3211_1442	LG3211_4245	Cyclase family protein.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.953
ALN90418.1	kynU	LG3211_1442	LG3211_2671	Cyclase family protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.	0.975
ALN93177.1	hppD	LG3211_4242	LG3211_4241	Transcriptional regulator marR/emrR family.	4-hydroxyphenylpyruvate dioxygenase.	0.846
ALN93177.1	kynA	LG3211_4242	LG3211_4245	Transcriptional regulator marR/emrR family.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.523
ALN93179.1	kynA	LG3211_4244	LG3211_4245	H+ symporter family protein.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.475
ALN93181.1	kynA	LG3211_4246	LG3211_4245	Conserved repeat domain protein.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.487
ALN94184.1	kynA	LG3211_5252	LG3211_4245	Cyclase family protein.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.447
ALN94184.1	kynU	LG3211_5252	LG3211_2671	Cyclase family protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.	0.719
hppD	ALN93177.1	LG3211_4241	LG3211_4242	4-hydroxyphenylpyruvate dioxygenase.	Transcriptional regulator marR/emrR family.	0.846
hppD	kynA	LG3211_4241	LG3211_4245	4-hydroxyphenylpyruvate dioxygenase.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.534
kynA	ALN90418.1	LG3211_4245	LG3211_1442	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	Cyclase family protein.	0.953
kynA	ALN93177.1	LG3211_4245	LG3211_4242	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	Transcriptional regulator marR/emrR family.	0.523
kynA	ALN93179.1	LG3211_4245	LG3211_4244	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	H+ symporter family protein.	0.475
kynA	ALN93181.1	LG3211_4245	LG3211_4246	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	Conserved repeat domain protein.	0.487
kynA	ALN94184.1	LG3211_4245	LG3211_5252	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	Cyclase family protein.	0.447
kynA	hppD	LG3211_4245	LG3211_4241	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	4-hydroxyphenylpyruvate dioxygenase.	0.534
kynA	kynU	LG3211_4245	LG3211_2671	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.	0.987
kynA	trpA	LG3211_4245	LG3211_2188	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.810
kynA	trpB	LG3211_4245	LG3211_2187	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.800
kynU	ALN90418.1	LG3211_2671	LG3211_1442	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.	Cyclase family protein.	0.975

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