Exig_0002 protein (Exiguobacterium sibiricum)

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Exig_0002

DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (377 aa)

Predicted Functional Partners:

Exig_0774

0.993

polA

0.992

Exig_2216

0.991

dnaA

0.989

dnaX

0.987

Exig_2847

0.987

Exig_0025

0.984

mutS

0.972

polC

0.941

Exig_0423

0.931

Your Current Organism:

Exiguobacterium sibiricum

NCBI taxonomy Id: 262543
Other names: E. sibiricum 255-15, Exiguobacterium sibiricum 255-15, Exiguobacterium sibiricum str. 255-15, Exiguobacterium sibiricum strain 255-15, Exiguobacterium sp. 255-15, Exiguobacterium strain 255-15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Exig_0002	Exig_0025	Exig_0002	Exig_0025	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	KEGG: bha:BH0044 DNA polymerase III subunit delta'.	0.984
Exig_0002	Exig_0423	Exig_0002	Exig_0423	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: gtn:GTNG_2069 DNA-damage repair protein, ImpB/MucB/SamB family; Belongs to the DNA polymerase type-Y family.	0.931
Exig_0002	Exig_0774	Exig_0002	Exig_0774	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: bld:BLi02748 DNA polymerase III subunit delta.	0.993
Exig_0002	Exig_2216	Exig_0002	Exig_2216	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III, alpha subunit; KEGG: btk:BT9727_4333 DNA polymerase III DnaE; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit.	0.991
Exig_0002	Exig_2847	Exig_0002	Exig_2847	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: cpe:CPE1401 probable DNA polymerase III epsilon chain.	0.987
Exig_0002	dnaA	Exig_0002	Exig_0001	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.	0.989
Exig_0002	dnaX	Exig_0002	Exig_0018	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.987
Exig_0002	mutS	Exig_0002	Exig_1044	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.	0.972
Exig_0002	polA	Exig_0002	Exig_2202	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.992
Exig_0002	polC	Exig_0002	Exig_1842	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.941
Exig_0025	Exig_0002	Exig_0025	Exig_0002	KEGG: bha:BH0044 DNA polymerase III subunit delta'.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.984
Exig_0025	Exig_0774	Exig_0025	Exig_0774	KEGG: bha:BH0044 DNA polymerase III subunit delta'.	TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: bld:BLi02748 DNA polymerase III subunit delta.	0.985
Exig_0025	Exig_2216	Exig_0025	Exig_2216	KEGG: bha:BH0044 DNA polymerase III subunit delta'.	DNA polymerase III, alpha subunit; KEGG: btk:BT9727_4333 DNA polymerase III DnaE; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit.	0.986
Exig_0025	Exig_2847	Exig_0025	Exig_2847	KEGG: bha:BH0044 DNA polymerase III subunit delta'.	PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: cpe:CPE1401 probable DNA polymerase III epsilon chain.	0.981
Exig_0025	dnaX	Exig_0025	Exig_0018	KEGG: bha:BH0044 DNA polymerase III subunit delta'.	DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.937
Exig_0025	polA	Exig_0025	Exig_2202	KEGG: bha:BH0044 DNA polymerase III subunit delta'.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.490
Exig_0025	polC	Exig_0025	Exig_1842	KEGG: bha:BH0044 DNA polymerase III subunit delta'.	DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.920
Exig_0423	Exig_0002	Exig_0423	Exig_0002	DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: gtn:GTNG_2069 DNA-damage repair protein, ImpB/MucB/SamB family; Belongs to the DNA polymerase type-Y family.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.931
Exig_0423	Exig_2216	Exig_0423	Exig_2216	DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: gtn:GTNG_2069 DNA-damage repair protein, ImpB/MucB/SamB family; Belongs to the DNA polymerase type-Y family.	DNA polymerase III, alpha subunit; KEGG: btk:BT9727_4333 DNA polymerase III DnaE; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit.	0.559
Exig_0423	Exig_2847	Exig_0423	Exig_2847	DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: gtn:GTNG_2069 DNA-damage repair protein, ImpB/MucB/SamB family; Belongs to the DNA polymerase type-Y family.	PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: cpe:CPE1401 probable DNA polymerase III epsilon chain.	0.506

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