STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnmVPrimase/topoisomerase like protein; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. (186 aa)    
Predicted Functional Partners:
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.904
Exig_0034
3D domain protein; PFAM: protein of unknown function DUF348; 3D domain protein; G5 domain protein; KEGG: gtn:GTNG_0032 hypothetical protein.
 
   
 0.817
Exig_0033
TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: bcl:ABC0067 deoxyribonuclease, TatD family.
  
  
 0.726
ispE
4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
  
  
 0.640
Exig_0037
PFAM: protein of unknown function DUF1021; KEGG: sha:SH2517 hypothetical protein.
       0.603
Exig_2224
PFAM: 3D domain protein; SH3 type 3 domain protein; SMART: SH3 domain protein; KEGG: bld:BLi02213 YocH.
 
   
 0.593
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
       0.554
Exig_0039
Purine operon repressor, PurR; TIGRFAM: pur operon repressor; PFAM: phosphoribosyltransferase; purine repressor; KEGG: gka:GK0040 purine operon repressor.
 
     0.531
Exig_1953
PFAM: RNA-binding S4 domain protein; KEGG: bcy:Bcer98_2546 RNA-binding S4 domain protein.
  
   
 0.509
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
 
     0.456
Your Current Organism:
Exiguobacterium sibiricum
NCBI taxonomy Id: 262543
Other names: E. sibiricum 255-15, Exiguobacterium sibiricum 255-15, Exiguobacterium sibiricum str. 255-15, Exiguobacterium sibiricum strain 255-15, Exiguobacterium sp. 255-15, Exiguobacterium strain 255-15
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