STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Exig_0920PFAM: Transketolase central region; Transketolase domain protein; KEGG: bha:BH2762 branched-chain alpha-keto acid dehydrogenase E1. (327 aa)    
Predicted Functional Partners:
Exig_0919
PFAM: dehydrogenase E1 component; KEGG: bwe:BcerKBAB4_4003 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring).
 0.999
Exig_0921
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: bpu:BPUM_2142 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.
 
 0.998
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.995
pdhA-2
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.995
Exig_0918
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: bld:BLi02583 dihydrolipoamide dehydrogenase.
 
 0.993
Exig_0916
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: gka:GK2381 leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.979
Exig_2008
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: bcy:Bcer98_2671 dihydrolipoamide dehydrogenase.
 
 0.975
Exig_0382
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: bha:BH0216 pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase).
 
 0.973
Exig_2009
Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: bha:BH2653 branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.928
Exig_0383
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: oih:OB2875 pyruvate dehydrogenase E2.
 
 0.925
Your Current Organism:
Exiguobacterium sibiricum
NCBI taxonomy Id: 262543
Other names: E. sibiricum 255-15, Exiguobacterium sibiricum 255-15, Exiguobacterium sibiricum str. 255-15, Exiguobacterium sibiricum strain 255-15, Exiguobacterium sp. 255-15, Exiguobacterium strain 255-15
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.