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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhA-2Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (360 aa)    
Predicted Functional Partners:
Exig_0384
PFAM: Transketolase central region; Transketolase domain protein; KEGG: gtn:GTNG_1911 pyruvate decarboxylase beta subunit-like protein.
 0.999
Exig_2010
PFAM: Transketolase central region; Transketolase domain protein; KEGG: bha:BH2654 pyruvate dehydrogenase E1 (lipoamide) beta subunit.
 0.999
Exig_2009
Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: bha:BH2653 branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.996
Exig_0920
PFAM: Transketolase central region; Transketolase domain protein; KEGG: bha:BH2762 branched-chain alpha-keto acid dehydrogenase E1.
 0.995
Exig_0383
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: oih:OB2875 pyruvate dehydrogenase E2.
 
 0.990
Exig_2008
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: bcy:Bcer98_2671 dihydrolipoamide dehydrogenase.
 
 
 0.988
Exig_0382
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: bha:BH0216 pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase).
 
 
 0.966
Exig_0918
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: bld:BLi02583 dihydrolipoamide dehydrogenase.
 
 
 0.964
Exig_2211
TIGRFAM: pyruvate kinase; PFAM: PEP-utilising protein mobile region; Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: bha:BH3163 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.940
Exig_0607
KEGG: lwe:lwe1422 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL.
   
 
 0.922
Your Current Organism:
Exiguobacterium sibiricum
NCBI taxonomy Id: 262543
Other names: E. sibiricum 255-15, Exiguobacterium sibiricum 255-15, Exiguobacterium sibiricum str. 255-15, Exiguobacterium sibiricum strain 255-15, Exiguobacterium sp. 255-15, Exiguobacterium strain 255-15
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