Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Exig_2191PFAM: Catalase domain protein; KEGG: bcl:ABC1283 catalase; Belongs to the catalase family. (489 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
   
 
  0.904
Exig_2999
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.792
Exig_0858
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 0.755
msrA
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 
 0.731
msrA-2
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 
 0.731
Exig_1724
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: bsu:BSU18450 glutamate synthase (large subunit).
  
  
 0.653
Exig_3000
TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bcy:Bcer98_0314 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.638
Exig_2352
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: bha:BH3486 butyryl-CoA dehydrogenase.
  
 0.635
Exig_2827
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: cbe:Cbei_2945 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Belongs to the sulfur carrier protein TusA family.
  
 
 0.625
Exig_1387
PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: bsu:BSU13040 nitric oxide dioxygenase; Belongs to the globin family.
  
   
 0.609
Your Current Organism:
Exiguobacterium sibiricum
NCBI taxonomy Id: 262543
Other names: E. sibiricum 255-15, Exiguobacterium sibiricum 255-15, Exiguobacterium sibiricum str. 255-15, Exiguobacterium sibiricum strain 255-15, Exiguobacterium sp. 255-15, Exiguobacterium strain 255-15
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