STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Exig_2829KEGG: gka:GK2684 hypothetical protein. (394 aa)    
Predicted Functional Partners:
Exig_2338
FeS assembly ATPase SufC; KEGG: btk:BT9727_4692 iron regulated ABC transporter, ATP-binding protein; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase.
  
 
 0.917
Exig_2336
Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 
 0.768
Exig_2335
TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; KEGG: btl:BALH_4512 NifU family protein.
  
  
 0.734
Exig_2834
KEGG: gka:GK2678 hypothetical protein.
  
    0.732
mprF-2
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
       0.727
Exig_2833
PFAM: glycosyl transferase family 2; KEGG: gka:GK2679 dolichyl-phosphate mannose synthase.
       0.725
Exig_2832
PFAM: sulfatase; type I phosphodiesterase/nucleotide pyrophosphatase; metalloenzyme domain protein; KEGG: gka:GK2680 hypothetical protein.
       0.719
Exig_2830
PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: gka:GK2682 nucleotide sugar epimerase.
       0.701
Exig_2836
KEGG: gka:GK2676 hypothetical protein.
       0.698
Exig_2835
PFAM: iron permease FTR1; KEGG: gka:GK2677 hypothetical protein.
     
 0.686
Your Current Organism:
Exiguobacterium sibiricum
NCBI taxonomy Id: 262543
Other names: E. sibiricum 255-15, Exiguobacterium sibiricum 255-15, Exiguobacterium sibiricum str. 255-15, Exiguobacterium sibiricum strain 255-15, Exiguobacterium sp. 255-15, Exiguobacterium strain 255-15
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