Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
Exig_3000TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bcy:Bcer98_0314 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (509 aa)    
Predicted Functional Partners:
Exig_2999
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
 
  
 0.998
Exig_2827
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: cbe:Cbei_2945 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Belongs to the sulfur carrier protein TusA family.
     
 0.702
Exig_2191
PFAM: Catalase domain protein; KEGG: bcl:ABC1283 catalase; Belongs to the catalase family.
  
  
 0.638
Exig_1387
PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: bsu:BSU13040 nitric oxide dioxygenase; Belongs to the globin family.
  
   
 0.612
Exig_0858
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.601
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.570
Exig_2716
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
      
 0.551
Exig_2247
PFAM: Ferritin Dps family protein; KEGG: bwe:BcerKBAB4_4875 ferritin Dps family protein; Belongs to the Dps family.
  
  
 0.492
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.481
Exig_2164
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: bcl:ABC2668 thioredoxin; Belongs to the thioredoxin family.
  
  
 0.470
Your Current Organism:
Exiguobacterium sibiricum
NCBI taxonomy Id: 262543
Other names: E. sibiricum 255-15, Exiguobacterium sibiricum 255-15, Exiguobacterium sibiricum str. 255-15, Exiguobacterium sibiricum strain 255-15, Exiguobacterium sp. 255-15, Exiguobacterium strain 255-15
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