STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SC1_011703-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (409 aa)    
Predicted Functional Partners:
SC1_03897
enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.996
SC1_04295
enoyl-CoA hydratase.
  
 0.996
SC1_01169
3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
  0.971
SC1_03875
3-hydroxybutyryl-CoA dehydrogenase.
  
 0.955
SC1_04232
Hypothetical protein.
 
 0.955
SC1_01172
Lignostilbene-alpha,beta-dioxygenase and related enzymes.
 
     0.939
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.919
SC1_02049
Citrate synthase; Belongs to the citrate synthase family.
   
 0.909
SC1_00388
succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B.
  
 
 0.906
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 
 0.900
Your Current Organism:
Sphingopyxis sp. C1
NCBI taxonomy Id: 262667
Other names: S. sp. C-1, Sphingopyxis sp. C-1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.