STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SC1_01890Glutathione reductase; Maintains high levels of reduced glutathione. (448 aa)    
Predicted Functional Partners:
SC1_02426
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.999
SC1_04220
Acetoin dehydrogenase E1 component alpha-subunit.
 
 0.995
SC1_04178
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit.
  
 0.994
SC1_03291
2-oxoglutarate dehydrogenase E1 component.
  
 0.972
SC1_01781
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
 0.948
SC1_01919
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.944
SC1_03290
Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.933
SC1_00049
Thioredoxin domain-containing protein EC-YbbN; FIG000875.
  
 
 0.932
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
  
  
 0.922
SC1_00249
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
 
  
 0.918
Your Current Organism:
Sphingopyxis sp. C1
NCBI taxonomy Id: 262667
Other names: S. sp. C-1, Sphingopyxis sp. C-1
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