STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (276 aa)    
Predicted Functional Partners:
SC1_00030
Proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 0.855
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.810
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.802
SC1_03249
Alkaline phosphatase; Alkaline phosphatase with broad substrate specificity.
       0.723
SC1_03251
RNA binding methyltransferase FtsJ like.
       0.614
SC1_00994
Glutamate synthase [NADPH] large chain.
 
   
 0.577
SC1_03250
Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase.
       0.549
SC1_01216
Hypothetical protein; Not a Proline racemase, nor 4-hydroxyproline epimerase [missing catalytic residues]; Belongs to the proline racemase family.
     
 0.526
SC1_04165
4-hydroxyproline epimerase; Belongs to the proline racemase family.
     
 0.526
SC1_03252
tspO and MBR like proteins.
       0.519
Your Current Organism:
Sphingopyxis sp. C1
NCBI taxonomy Id: 262667
Other names: S. sp. C-1, Sphingopyxis sp. C-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.