STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaAChromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (456 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III beta subunit; Identified by sequence similarity; putative; ORF located using Blastx;COG0592.
  
 
 0.994
dnaB
Replicative DNA helicase; Identified by sequence similarity; putative; ORF located using Blastx;COG0305.
 
 
 
 0.940
himA
Bacterial nucleoid DNA-binding protein; Identified by sequence similarity; putative; ORF located using Blastx;COG0776; Belongs to the bacterial histone-like protein family.
    
 
 0.663
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
  
 0.633
MS53_0003
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx;COG2501.
  
    0.618
MS53_0528
Identified by sequence similarity; putative; ORF located using Blastx;COG0258.
     
 0.603
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.592
MS53_0525
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx.
    
 
 0.592
pgk
Phosphoglycerate kinase; Identified by sequence similarity; putative; ORF located using Blastx;COG0126.
      
 0.590
recR
Putative recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
 
  
 0.566
Your Current Organism:
Mycoplasma synoviae
NCBI taxonomy Id: 262723
Other names: M. synoviae 53, Mycoplasma synoviae 53, Mycoplasma synoviae str. 53, Mycoplasma synoviae strain 53
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.